Title of article :
A 1,5-benzothiazepine synthesis
Author/Authors :
Phippen، نويسنده , , Christopher B.W. and McErlean، نويسنده , , Christopher S.P.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
The pharmaceutically active compound (±)-thiazesim was synthesized in four steps and 62% overall yield. This new approach to biologically relevant benzothiazepine ring systems features the use of water as a solvent, co-solvent or catalyst in three of the four steps.
Keywords :
benzothiazepine , heterocyclic chemistry , aqueous chemistry , N-Acylpyrrole
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
