Author/Authors :
Tadesse، نويسنده , , Margey and Svenson، نويسنده , , Johan and Jaspars، نويسنده , , Marcel and Strّm، نويسنده , , Morten B. and Abdelrahman، نويسنده , , Mostafa H. and Andersen، نويسنده , , Jeanette H. and Hansen، نويسنده , , Espen and Kristiansen، نويسنده , , Per E. and Stensvهg، نويسنده , , Klara and Haug، نويسنده , , Tor، نويسنده ,
Abstract :
Synoxazolidinone C is a new member of the synoxazolidinone family of compounds which are dibrominated guanidinium 4-oxazolidinones isolated from the sub-Arctic ascidian Synoicum pulmonaria. The compound was isolated along with synoxazolidinones A and B from the same ascidian extract. Spectroscopic methods revealed that the synoxazolidinone C differed from the other synoxazolidinones by an unprecedented bicyclic partial structure, containing an additional pyrrolidine ring. Synoxazolidinone C exhibited both antibacterial and anticancer activities.
Keywords :
4-Oxazolidinone , Synoxazolidinone , Synoicum pulmonaria , Antibacterial , Anticancer
