Title of article
Total synthesis and biological evaluation of marinopyrrole A and analogs
Author/Authors
Nicolaou، نويسنده , , K.C. and Simmons، نويسنده , , Nicholas L. and Chen، نويسنده , , Jason S. and Haste، نويسنده , , Nina M. and Nizet، نويسنده , , Victor، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
2041
To page
2043
Abstract
A five-step total synthesis of the antibiotic marinopyrrole A (1) is described. The developed synthetic technology enabled the synthesis of several marinopyrrole A analogs whose antibacterial properties against methicillin-resistant Staphylococcus aureus TCH1516 were evaluated.
Keywords
Clauson-Kaas reaction , total synthesis , Atropisomers , marine natural products
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877774
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