Title of article :
NMR studies of the reversible and regioselective lactonization of α-2,8-linked trisialic acid in aqueous acid
Author/Authors :
Eckert، نويسنده , , Timothy K. Lu، نويسنده , , Chun-Ping and Chen، نويسنده , , Chien-Sheng and Wu، نويسنده , , Shih-Hsiung and Gervay-Hague، نويسنده , , Jacquelyn، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
The pH dependent lactonization of trisialic acid was examined using NMR and CE techniques. The combined studies indicate that lactonization is a dynamic, pH dependent process that occurs with preferential lactonization between the carbonyl of the central residue and the reducing end C-9 hydroxyl group.
Keywords :
Nuclear magnetic resonance , Capillary electrophoresis , Sialic acid , Lactonization , regioselectivity
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
