Title of article :
Microwave-promoted tandem reactions for the synthesis of bicyclic γ-lactams
Author/Authors :
Dennis McGonagle، نويسنده , , Fiona I. and Brown، نويسنده , , Lindsay and Cooke، نويسنده , , Andrew and Sutherland، نويسنده , , Andrew، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A microwave-promoted three-step tandem process for the synthesis of bicyclic γ-lactams is developed. In all cases examined this led to significantly faster tandem processes producing the bicyclic γ-lactams more cleanly and reproducibly compared to standard thermal conditions.
Keywords :
Tandem reactions , Ring closing metathesis , microwave synthesis , Kharasch cyclisation , Overman rearrangement
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters