Title of article
Preparation of a chiral azadiene for the synthesis of 5-aza analogues of angucyclinones
Author/Authors
Sissouma، نويسنده , , Drissa and Dequirez، نويسنده , , Geoffroy and Collet، نويسنده , , Sylvain and Guingant، نويسنده , , André، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
2336
To page
2339
Abstract
We have developed an efficient synthesis of both enantiomers of a key azadiene for the preparation of 5-aza analogues of angucyclinones through a hetero Diels–Alder reaction. These dienes were efficiently prepared via a 4-step procedure from known and readily available chiral diketoesters.
Keywords
Chiral azadiene , Enaminone , hetero Diels–Alder reaction , Ester hydrolysis , Aza-angucyclinone
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877979
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