Title of article
Simple protocol for enhanced (E)-selectivity in Julia–Kocienski reaction
Author/Authors
Posp??il، نويسنده , , Ji??، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
2348
To page
2352
Abstract
A short and efficient Julia–Kocienski olefination protocol, based upon the use of chelating agents (18-crown-6 or TDA-1 for K+; 12-crown-4 or HMPA for Li+), was developed. This protocol enhances the (E)-selectivity of the reaction and the desired olefins are obtained generally with >10:1 (E/Z)-selectivity.
Keywords
chelation , Julia–Kocienski reaction , olefins , Selectivity
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877987
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