Title of article
A new and practical boronic acid catalyzed intramolecular cyclodehydration of ureas for the synthesis of LFA-1 antagonists
Author/Authors
Frutos، نويسنده , , Rogelio P. and Tampone، نويسنده , , Thomas A. Mulder، نويسنده , , Jason A. and Xu، نويسنده , , Yibo and Reeves، نويسنده , , Diana and Wang، نويسنده , , Xiaojun and Zhang، نويسنده , , Li and Krishnamurthy، نويسنده , , Dhileepkumar and Senanayake، نويسنده , , Chris H.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
2465
To page
2467
Abstract
A streamlined and practical approach to 1H-imidazo[1,2-α]imidazol-2-one LFA-1 antagonist (1) that features as the key step a novel intramolecular boronic acid catalyzed cyclocondensation of a urea and an amide is reported.
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878068
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