Title of article :
New very mild conditions for the opening of an epoxide assisted by a neighboring carbonyl group
Author/Authors :
Walther، نويسنده , , Alexandre and Josien-Lefebvre، نويسنده , , Delphine and Le Drian، نويسنده , , Claude، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
An epoxide is opened stereo- and regio-selectively by 1,3-endo migration of a phenylthiogroup in almost neutral conditions. The thioether is then reduced to give the alcohol corresponding to the starting epoxide in an excellent yield.
Keywords :
Epoxide opening , Intramolecular migration , regioselectivity , Zinc iodide , Iodine catalysis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
