Title of article
An efficient copper-free Pd(OAc)2/Ruphos-catalyzed Sonogashira coupling of 1-chloroisoquinolines in the formation of 1-alkynyl-3-substituted isoquinolines
Author/Authors
Prabakaran، نويسنده , , K. and Nawaz Khan، نويسنده , , F. and Jin، نويسنده , , Jong Sung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
2566
To page
2570
Abstract
An efficient, copper-free Sonogashira coupling reaction of 1-chloroisoquinolines and terminal alkynes, catalyzed by Pd(OAc)2/Ruphos, in the presence of Et3N and tetrahydrofuran leads to the formation of 1-alkynyl-3-substituted isoquinolines in good yields.
Keywords
1-Alkynyl-3-substituted isoquinolines , copper-free , Sonogashira coupling , Ruphos
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878148
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