Title of article
Diastereoselective synthesis of tetrasubstituted-octahydro-3,6-diazacarbazoles and tetrasubstituted-3,6-diazacarbazoles via double Pictet–Spengler reaction
Author/Authors
Shumaila، نويسنده , , Abdullah M.A. and Puranik، نويسنده , , Vedavati G. and Kusurkar، نويسنده , , Radhika S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
2661
To page
2663
Abstract
Pictet–Spengler condensation of 2,5-bis(2-phenyl-1-aminoethyl)pyrrole using glacial acetic acid afforded only one diastereomer of unreported tetrasubstituted-octahydro-3,6-diazacarbazoles. These were readily dehydrogenated to tetrasubstituted-3,6-diazacarbazoles. The stereoselectivity in the Pictet–Spengler reaction has been demonstrated using single crystal X-ray analysis.
Keywords
Tetrasubstituted-octahydro-3 , 6-diazacarbazoles , 2 , Diasteroselective Pictet–Spengler reaction , 5-Bis(2-phenyl-1-aminoethyl)pyrrole , Tetrasubstituted-3 , 6-diazacarbazoles , Glacial acetic acid
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878225
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