Title of article
Asymmetric organocatalytic Michael/α-alkylation reaction of α,β-unsaturated aldehyde with chloroacetophenone
Author/Authors
Li، نويسنده , , Wenjun and Li، نويسنده , , Xin and Ye، نويسنده , , Tingting and Wu، نويسنده , , Wenbin and Liang، نويسنده , , Xinmiao and Ye، نويسنده , , Jinxing، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
2715
To page
2718
Abstract
Asymmetric organocatalytic Michael/α-alkylation reactions of α,β-unsaturated aldehydes with chloroacetophenones have been developed. The biologically useful cyclopropane motifs were synthesized with high yields and up to >99% ee, >30:1 dr through Jørgensen–Hayashi catalyst under mild conditions.
Keywords
?-Unsaturated aldehyde , ? , organocatalysis , Tandem reaction , enantioselective , Asymmetric catalysis
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878267
Link To Document