Author/Authors :
Wang، نويسنده , , Gang-Qiang and Wei، نويسنده , , Kun and Zhang، نويسنده , , Lin and Feng، نويسنده , , Tao and Wang، نويسنده , , Fei and Wang، نويسنده , , Qiu-An and Liu، نويسنده , , Ji-Kai، نويسنده ,
Abstract :
A one-step biomimetic synthesis of racemic linderspirone and bi-liderone from methyllinderone has been achieved, which probably reflects the biosynthesis of the natural products. There are few naturally occurring substances that appear to be formed by a [4+4] or [4+2] cycloaddition. We proposed that the [4+4] dimerization of methyllinderone proceeds via a stepwise mechanism involving a diradical intermediate.
Keywords :
biomimetic , Methyllinderone , Bi-liderone , Linderspirone , Synthesis
