Title of article :
Synthesis of new spin labels for Cu-free click conjugation
Author/Authors :
K?lai، نويسنده , , Tam?s and Fleissner، نويسنده , , Mark R. and Jek?، نويسنده , , J?zsef and Hubbell، نويسنده , , Wayne L. and Hideg، نويسنده , , K?lm?n، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
New pyrroline nitroxides attached to a terminal acetylenic sulfone, a dibenzocyclooctyne or a cyclooctyne carboxylic acid were synthesized and tested in Cu-free click reactions to conjugate these new spin labels with 4-azido-TEMPO, azidophenylalanine and an azidophenylalanine-containing protein.
Keywords :
click chemistry , Free radicals , spin labeling , Acetylenes , amino acids
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
