Title of article
Ruthenium-catalyzed asymmetric transfer hydrogenation of ketones in ethanol
Author/Authors
Lundberg، نويسنده , , Helena and Adolfsson، نويسنده , , Hans، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
2754
To page
2758
Abstract
A ruthenium catalyst formed in situ by combining [Ru(p-cymene)Cl2]2 and an amino acid hydroxy-amide was found to catalyze efficiently the asymmetric reduction of aryl alkyl ketones under transfer hydrogenation conditions using ethanol as the hydrogen donor. The secondary alcohol products were obtained in moderate to good yields and with good to excellent enantioselectivity (up to 97% ee).
Keywords
Asymmetric catalysis , Reduction , amino acids , Ruthenium
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878309
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