Title of article :
Solvent-free protocol for amide bond formation via trapping of nascent phosphazenes with carboxylic acids
Author/Authors :
Sathishkumar، نويسنده , , Murugan and Shanmugavelan، نويسنده , , Poovan and Nagarajan، نويسنده , , Sangaraiah and Maheswari، نويسنده , , Murugesan and Dinesh، نويسنده , , Murugan and Ponnuswamy، نويسنده , , K. Alagusundaram، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Pages :
4
From page :
2830
To page :
2833
Abstract :
A solvent-free synthesis of amides via the coupling of phosphazenes with carboxylic acids is reported. Increasing the rate of heating either by microwave irradiation or conventional heating results in multifold increase in the rate of amide bond formation. Synthesis of a library of amides including a potent antitumour candidate has been accomplished.
Keywords :
MW-irradiation/Glycerol bath , solvent-free , amide
Journal title :
Tetrahedron Letters
Serial Year :
2011
Journal title :
Tetrahedron Letters
Record number :
1878369
Link To Document :
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