Title of article
Solvent-free protocol for amide bond formation via trapping of nascent phosphazenes with carboxylic acids
Author/Authors
Sathishkumar، نويسنده , , Murugan and Shanmugavelan، نويسنده , , Poovan and Nagarajan، نويسنده , , Sangaraiah and Maheswari، نويسنده , , Murugesan and Dinesh، نويسنده , , Murugan and Ponnuswamy، نويسنده , , K. Alagusundaram، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
2830
To page
2833
Abstract
A solvent-free synthesis of amides via the coupling of phosphazenes with carboxylic acids is reported. Increasing the rate of heating either by microwave irradiation or conventional heating results in multifold increase in the rate of amide bond formation. Synthesis of a library of amides including a potent antitumour candidate has been accomplished.
Keywords
MW-irradiation/Glycerol bath , solvent-free , amide
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878369
Link To Document