Title of article :
The stereoselective total synthesis of (+)-18-(6S,9R,10R)-bovidic acid
Author/Authors :
Yadav، نويسنده , , J.S. and Ramesh، نويسنده , , K. and Subba Reddy، نويسنده , , U.V. and Subba Reddy، نويسنده , , B.V. and Ghamdi، نويسنده , , Ahamad Al Khazim Al Ghamdi، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
An expedient stereoselective total synthesis of 18-carbon (+)-(6S,9R,10R)-bovidic acid, isolated from the pelage and skin of a gaur B. frontalis is described using l-proline catalysed sequential α-aminoxylation and Horner–Wadsworth–Emmons olefination of aldehyde, cross metathesis and tandem Sharpless asymmetric dihydroxylation-SN2 cyclization reaction as the key steps.
Keywords :
Bovidic acid , MacMillan ?-hydroxylation , Horner–Wadsworth–Emmons reaction , Cross metathesis , Tandem dihydroxylation-SN2 cyclization
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
