Title of article
Ratiometric detection of cysteine by a ferrocenyl Michael acceptor
Author/Authors
Lim، نويسنده , , Soo-Yeon and Kim، نويسنده , , Hae-Jo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
2
From page
3189
To page
3190
Abstract
An activated ferrocenyl enone (1) by an intramolecular hydrogen bond was utilized as a Michael acceptor type of chemodosimeter for cysteine. The probe has shown selective response toward cysteine over other natural amino acids through the Michael addition reaction of a cysteinyl thiol group to 1. When cysteine was added, the prominent color change of 1 was observed so that submillimolar concentrations of cysteine were detectable by the naked eye.
Keywords
Hydrogen bond , Cysteine , Naked-eye detection , Ferrocene
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878530
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