Title of article :
An efficient indium-mediated 2-bromoallylation of aldehydes at low temperature in aqueous DMF
Author/Authors :
Kim، نويسنده , , Yu Mi and Lee، نويسنده , , Sangku and Kim، نويسنده , , Sung-Hwan and Kim، نويسنده , , Jae Nyoung، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
An efficient synthesis of 2-bromohomoallylic alcohols was carried out via an indium-mediated Barbier-type 2-bromoallylation of aldehydes in moderate yields. The reaction was performed at low temperature (−20 °C) in aqueous DMF in order to minimize decomposition of 2-bromoallylindium reagent to allene.
Keywords :
2-Bromoallylation , Allene , Indium , Barbier reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
