Title of article
Chiral Pd-catalyzed enantioselective Friedel–Crafts reaction of indoles with γ,δ-unsaturated β-keto phosphonates
Author/Authors
Kang، نويسنده , , Young Ku and Kwon، نويسنده , , Bo Kyung and Mang، نويسنده , , Joo Yang and Kim، نويسنده , , Dae Young، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
3247
To page
3249
Abstract
The catalytic enantioselective Friedel–Crafts alkylation reaction promoted by chiral palladium complexes is described. The treatment of indoles with γ,δ-unsaturated β-keto phosphonates under the mild reaction conditions afforded the corresponding Friedel–Crafts alkylation adducts with excellent enantioselectivities (up to 99% ee).
Keywords
?-Unsaturated ?-keto phosphonates , Asymmetric catalysis , Friedel–Crafts reaction , Chiral palladium catalysts , ? , indoles
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878563
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