Title of article
First total synthesis of tenuifolin via PIFA mediated oxidative biaryl coupling
Author/Authors
Tang، نويسنده , , Changhua and Li، نويسنده , , Ziyuan and Wang، نويسنده , , Yiyun and Xu، نويسنده , , Jinyi and Kong، نويسنده , , Lingyi and Yao، نويسنده , , Hequan and Wu، نويسنده , , Xiaoming، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
3275
To page
3278
Abstract
The first total synthesis of a sesquiterpenoid, tenuifolin, was achieved in seven linear steps. Phenyliodine(III) bis(trifluoacetate) (PIFA) mediated oxidative biaryl coupling was employed as a key step to construct the central seven-membered ring with a double bond. The double bond formation was also exploited.
Keywords
antitumor , Oxidative biaryl coupling , total synthesis , Tenuifolin , Wittig coupling
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878575
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