Title of article
A rapid and simple amine-catalyzed microwave-assisted isomerization of maleamides into fumaramides
Author/Authors
Vita Majce، نويسنده , , Vita and Ko?evar، نويسنده , , Marijan and Polanc، نويسنده , , Slovenko Polanc، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
3287
To page
3290
Abstract
An improved, efficient, and simple method for the synthesis of nonsymmetrical diamides of fumaric acid is reported. Starting from commercially available substrates, maleic diamides are formed in two steps, and then isomerized in a focused microwave reactor in acetonitrile as the solvent in the presence of a catalytic amount of piperidine, giving the corresponding fumaramides in high yields and purity.
Keywords
amine catalysis , Fumaramides , microwave irradiation , Isomerization
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878579
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