Title of article
Stereoselective synthesis of C-6 hydroxy tricyclic sulfone as a γ-secretase inhibitor
Author/Authors
Su، نويسنده , , Jing and Tang، نويسنده , , Haiqun and McKittrick، نويسنده , , Brian A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
3382
To page
3385
Abstract
The synthesis of a C-6 hydroxy tricyclic sulfone was described with two key reactions: the Suzuki coupling and the regioselective and stereoselective cis ring opening of the epoxide. Overall, the 14-step synthesis was achieved in 2.1% yield.
Keywords
regioselective , Suzuki coupling , stereoselective , cis Ring opening of an epoxide
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878625
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