Title of article :
Palladium catalyzed alkylation of indole via aliphatic C–H bond activation of tertiary amine
Author/Authors :
Ramachandiran، نويسنده , , K. and Muralidharan، نويسنده , , D. and Perumal، نويسنده , , P.T.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Alkylation of indoles has been achieved via Pd-catalyzed aliphatic C–H bond activation of tertiary amine coupling with indole followed by C–N bond cleavage and subsequent addition of indole. This method involves the migration of alkane chain from tertiary amine to indole.
Keywords :
C–H activation , PALLADIUM , 1 , 1-Bis-indolymethane , C–C coupling , Alkylation of indole
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters