Author/Authors :
Shao، نويسنده , , Changwei and Zhu، نويسنده , , Rui-Lin Luo، نويسنده , , Sheng and Zhang، نويسنده , , Qun and Wang، نويسنده , , Xinyan and Hu، نويسنده , , Yuefei، نويسنده ,
Abstract :
A simple combination of Cu2O and PhCO2H ‘on H2O’ has been developed as a highly practical and efficient catalytic system for copper(I)–catalyzed azide–alkyne cycloaddition (CuAAC). It not only provides a further evidence for the strategy of carboxylic acids-promoted CuAAC, but also offers significant advantages to CuAAC because Cu2O is one of the most stable and cheapest Cu(I) sources; PhCO2H is one of the structurally simplest bidentate ligands; and water is the most ‘green’ solvent.
Keywords :
Catalysis , Benzoic acid , click chemistry , Copper(I) oxide
