Author/Authors :
Alvarez-Manzaneda، نويسنده , , J.Enrique and Chahboun، نويسنده , , Rachid and Alvarez، نويسنده , , Esteban and Alvarez-Manzaneda، نويسنده , , Ramَn and Muٌoz، نويسنده , , Pedro E. and Jiménez، نويسنده , , Fermيn and Bouanou، نويسنده , , Hanane، نويسنده ,
Abstract :
The treatment of 2,3-epoxy primary alcohols with lead(IV) acetate (LTA) leads to α-acetoxy aldehydes or α-acetoxy ketones, through the nucleophilic ring-opening of an intermediate oxonium and the subsequent carbon–carbon bond cleavage. This reaction represents a new route to optically active α-hydroxy carbonyl compounds.
Keywords :
lead tetraacetate , Allyl alcohols , Hydroxycarbonyl compounds , asymmetric synthesis
