Title of article :
A concise synthesis of asymmetrical N,N′-disubstituted guanidines
Author/Authors :
O’Donovan، نويسنده , , Daniel H. and Rozas، نويسنده , , Isabel، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
We present a new and concise method for the preparation of asymmetrical N,N′-disubstituted guanidines starting from thiourea via the reaction of N-Boc-protected N′-alkyl/aryl substituted thioureas with an amine in the presence of mercury(II) chloride and triethylamine.
Keywords :
Thiourea , N , one-pot synthesis , Guanidine , N?-Dialkyl/aryl guanidine
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
