Title of article :
Grignard reagent induced tandem semipinacol rearrangement/ketone addition reaction of 20S-hydroxy-5α-pregnane-16(17)-epoxide
Author/Authors :
Huang، نويسنده , , Chunxi and Shi، نويسنده , , Yong and Lin، نويسنده , , Jing-Rong and Jin، نويسنده , , Rong-Hua and Tian، نويسنده , , Wei-Sheng، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A Grignard reagent induced tandem semipinacol rearrangement/chelation-controlled ketone addition process, which converts 20S-hydroxy-5α-pregnane-16(17)-epoxide into an unusual C20-substituted 17S-pregnane-3S,16R,20S-triol, is described.
Keywords :
Grignard reagent , Semipinacol rearrangement , Tandem reaction , Epoxide opening
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
