Title of article :
Three-component tandem reaction involving acid chlorides, terminal alkynes, and ethyl 2-amino-1H-indole-3-carboxylates: synthesis of highly diversified pyrimido[1,2-a]indoles via sequential Sonogashira and [3+3] cyclocondensation reactions
Author/Authors :
Gupta، نويسنده , , Sahaj and Sharma، نويسنده , , Sudhir K. and Mandadapu، نويسنده , , Anil K. and Gauniyal، نويسنده , , Harsh M. and Kundu، نويسنده , , Bijoy، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A simple, highly efficient three-component reaction involving acid chlorides, terminal alkynes, and ethyl 2-amino-1H-indole-3-carboxylates, for the synthesis of highly diversified pyrimido[1,2-a]indoles has been described. The salient feature of the reaction involves sequential Sonogashira and [3+3] cyclocondensation reactions.
Keywords :
2-a]indoles , multicomponent reaction , Sonogashira coupling , Alkynes , Ethyl 2-amino-1H-indole-3-carboxylate
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters