Title of article :
Tröger’s bases in the acronycine, benzo[a]acronycine, and benzo[b]acronycine series
Author/Authors :
Thomas Gaslonde، نويسنده , , Thomas and Léonce، نويسنده , , Stéphane and Pierré، نويسنده , , Alain and Pfeiffer، نويسنده , , Bruno and Michel، نويسنده , , Sylvie and Tillequin، نويسنده , , François، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Reaction of 11-aminoacronycine, 10-aminobenzo[a]acronycine, and 10-aminobenzo[b]acronycine with paraformaldehyde gave the corresponding Tröger’s bases 11, 14, and 16, respectively. The cytotoxic activity of those three new compounds was determined against L-1210 leukemia and KB-3-1 solid tumor cell lines, in comparison with their parent compounds, acronycine, benzo[a]acronycine, and benzo[b]acronycine.
Keywords :
Acronycine , Tr?ger’s base
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
