Title of article
An efficient non-ionic surfactant catalyzed multicomponent synthesis of novel benzylamino coumarin derivative via Mannich type reaction in aqueous media
Author/Authors
Kumar، نويسنده , , Atul Kumar Gupta، نويسنده , , Maneesh Kumar and Kumar، نويسنده , , Mukesh، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
4521
To page
4525
Abstract
An efficient non-ionic surfactant catalyzed multicomponent synthesis of novel benzylamino coumarin derivatives has been developed from secondary amines, aromatic aldehyde, and 4-hydroxy coumarin via Mannich type reaction in aqueous media. In this Mannich type reaction, surfactant forms stable colloidal medium to stabilize iminium ion which undergoes nucleophilic addition of 4-hydroxy coumarin to give benzylamino coumarin in very good yields.
Keywords
Mannich type reaction , 3-Substituted coumarin , water , Green synthesis , Non-ionic surfactant
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879114
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