Title of article :
Oxidative fragmentation of oxiranes to nitriles with hypervalent iodine(V) reagents in aqueous ammonia
Author/Authors :
Deshmukh، نويسنده , , Swapnil S. and Huddar، نويسنده , , Sameerana N. and Jadhav، نويسنده , , Ravindra R. and Akamanchi، نويسنده , , Krishnacharya G. Akamanchi، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Oxiranes undergo oxidative fragmentation when treated with hypervalent iodine(V) reagents particularly o-iodoxybenzoic acid in aqueous ammonia to give nitriles. The reaction goes via the formation of 1, 2-amino alcohols as intermediates followed by C–C bond cleavage.
Keywords :
o-Iodoxybenzoic acid , Oxiranes , Nitriles , Aqueous ammonia , Oxidative fragmentation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
