Author/Authors :
Nakashima، نويسنده , , Ken-ichi and Oyama، نويسنده , , Masayoshi and Ito، نويسنده , , Tetsuro and Witono، نويسنده , , Joko Ridho and Darnaedi، نويسنده , , Dedy and Tanaka، نويسنده , , Toshiyuki and Murata، نويسنده , , Jin and Iinuma، نويسنده , , Munekazu، نويسنده ,
Abstract :
Two novel Diels–Alder type adducts, melicodenines A (1) and B (2), were isolated from the leaves of Melicope denhamii (Seem.) T. G. Hartley and their structures were established by spectroscopic analyses, including extensive 2D NMR experiments. Compound 1 is a bisquinolinone alkaloid comprised of two N-methylflindersines (3), while compound 2 is the first naturally occurring quinolinone–acetophenone conjugate composed of 3 and an evodionol methyl ether (4).
Keywords :
Melicope denhamii , Rutaceae , Quinolinone , Diels–Alder cycloaddition
