Author/Authors :
Mondal، نويسنده , , Shyamal and Paira، نويسنده , , Rupankar and Maity، نويسنده , , Arindam and Naskar، نويسنده , , Subhendu and Sahu، نويسنده , , Krishnendu B. and Hazra، نويسنده , , Abhijit and Saha، نويسنده , , Pritam and Banerjee، نويسنده , , Sukdeb and Mondal، نويسنده , , Nirup B.، نويسنده ,
Abstract :
Basic alumina supported, solvent-free synthesis of novel oxazocines, medium size heterocycles, has been achieved in excellent yields by tandem C-alkylation followed by intramolecular O-alkylation of hydroxyquinoline/isoquinoline(s) with quinolinium salts under microwave irradiation. The method provides a facile and efficient route for the construction of polynuclear bridge-head oxazocines.
Keywords :
basic alumina , Tandem reaction , Bridged heterocycle , Quinolino/isoquinolinooxazocines , microwave irradiation