Title of article :
Stereoselective synthesis of (+)-radicamine B
Author/Authors :
Shankaraiah، نويسنده , , G. and Sateesh Chandra Kumar، نويسنده , , R. and Poornima، نويسنده , , B. and Babu، نويسنده , , K. Suresh، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A simple and efficient stereoselective synthesis of naturally occurring pyrrolidine alkaloid, radicamine B has been accomplished in 13 steps from the commercially available starting materials with an overall yield of 9.75%. The synthesis utilizes Sharpless asymmetric epoxidation and Horner–Wadsworth–Emmons (HWE) olefination as key steps.
Keywords :
Pyrrolidine alkaloids , HWE olefination , Sharpless asymmetric epoxidation , Radicamines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
