Title of article :
Hydroxyalkylation of 4,5,6,7-tetrahydroindole with polyfluorocarbonyl compounds as a route to 2-substituted indoles
Author/Authors :
Sigan، نويسنده , , Andrei L. and Gusev، نويسنده , , Dmitrii V. and Chkanikov، نويسنده , , Nikolai D. and Shmidt، نويسنده , , Elena Yu. and Ivanov، نويسنده , , Andrei V. and Mihaleva، نويسنده , , Al’bina I.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
The regioselective hydroxyalkylation of 4,5,6,7-tetrahydroindole at position 2 using highly electrophilic polyfluorocarbonyl compounds was performed for the first time. Oxidation of the products thus formed leads to indoles having 2-hydroxypolyfluoroalkyl and polyfluoroacyl groups.
Keywords :
Tetrahydroindole , 2-Substituted indoles , Hydroxyalkylation , Polyfluorocarbonyl compounds
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
