Author/Authors :
Ren، نويسنده , , Yunlai and Yan، نويسنده , , Mengjie and Zhao، نويسنده , , Shuang and Sun، نويسنده , , Yanpei and Wang، نويسنده , , Jianji and Yin، نويسنده , , Weiping and Liu، نويسنده , , Zhifei، نويسنده ,
Abstract :
Non-toxic K4[Fe(CN)6] was demonstrated to be effective as a green cyanating agent for the cyanation of alkyl halides using PPh3/Pd(OAc)2 as a catalyst system. The presented method allowed a series of benzyl chlorides to be smoothly cyanated in up to 88% yield. In order to avoid or suppress the deactivation of the catalyst, the reaction was required to be performed in a stringent inert ambiance.
Keywords :
cyanation , Benzyl chlorides , Potassium hexacyanoferrate(II) , PALLADIUM
