Title of article :
Sequential alkylation/gold-catalyzed annulation reactions of anilines with propargylic bromide derivatives
Author/Authors :
Alfonsi، نويسنده , , Maria and Arcadi، نويسنده , , Antonio and Chiarini، نويسنده , , Marco and Marinelli، نويسنده , , Fabio، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Preliminary results of sequential alkylation/gold-catalyzed annulation reactions of anilines with propargylic bromide derivatives to provide quinoline scaffolds are described. The efficiency of NaAuCl4·2H2O in the sequential procedure was investigated and compared with different transition metal salts and Au(I) complexes. Selectivity of the reaction of aniline derivatives with propargylic bromides has also been investigated.
Keywords :
Sequential reactions , gold catalysis , N-Propargylation , Quinolines , Intramolecular hydroarylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
