Author/Authors :
Aggarwal، نويسنده , , Amit and Singh، نويسنده , , Sunaina and Zhang، نويسنده , , Yazhou and Anthes، نويسنده , , Mariah and Samaroo، نويسنده , , Diana and Gao، نويسنده , , Ruomei and Drain، نويسنده , , Charles Michael، نويسنده ,
Abstract :
A water soluble zinc(II) phthalocyanine symmetrically appended with eight thioglucose units was synthesized from commercially available hexadecafluorophthalocyaninatozinc(II) by controlled nucleophilic substitution of the peripheral fluoro groups. The photophysical properties and cancer cell uptake studies of this nonhydrolysable thioglycosylated phthalocyanine are reported. The new compound has amphiphilic character, is chemically stable, and can potentially be used as a photosensitizer in photodynamic therapy.
Keywords :
quantum yield , Glucose , Phthalocyanine , fluorescence , photodynamic therapy
