Author/Authors :
Wen، نويسنده , , Yanmei and Wang، نويسنده , , Azhong and Jiang، نويسنده , , Huanfeng and Zhu، نويسنده , , Shifa and Huang، نويسنده , , Liangbin، نويسنده ,
Abstract :
An efficient procedure for regio- and stereoselective synthesis of a series of conjugated enynes by a simple Pd-catalyzed cross-coupling reaction of unactivated ethylenes and ethynyl bromide has been developed. The reaction proceeds smoothly in DMF to give the corresponding products in good to excellent yields. The protocol can tolerate a broad range of functional groups on the substrates.