Title of article
Application of flow chemistry to the reduction of nitriles to aldehydes
Author/Authors
Muٌoz، نويسنده , , Juan de M. and Alcلzar، نويسنده , , Jesْs and Hoz، نويسنده , , Antonio de la and Dيaz-Ortiz، نويسنده , , Angel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
6058
To page
6060
Abstract
Reduction of nitriles to aldehydes with diisobutylaluminium hydride (DIBAL-H) is an important transformation in organic chemistry. But the use of this reaction is limited for the lack of reproducibility due to the instability of the intermediates formed. In the current article we disclose the improvement of the reaction applying continuous flow technology.
Keywords
selective reduction , DIBAL-H , Microreactor , Flow chemistry
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879533
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