Author/Authors :
Humble، نويسنده , , Robert W. and Middleton، نويسنده , , Danielle F. and Banoub، نويسنده , , Joseph and Ewing، نويسنده , , David F. and Boa، نويسنده , , Andrew N. and Mackenzie، نويسنده , , Grahame، نويسنده ,
Abstract :
Bredinin (4-carbamoyl-1-β-d-ribofuranosylimidazolium-5-olate, 1) was synthesised by the formation of a malonamate from 2,3-isopropylidene-d-ribofuranosylamine and ethyl malonyl chloride, followed by a sequence involving amination, via reduction of an oxime, heterocycle formation and then deprotection.
