Title of article
Palladium-catalyzed direct 5-arylation of 1,3-dimethyluracil with aryl bromides: an electrophilic metalation–deprotonation with electrophilic arylpalladium intermediate
Author/Authors
Kim، نويسنده , , Ko Hoon and Lee، نويسنده , , Hyun Seung and Kim، نويسنده , , Jae Nyoung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
6
From page
6228
To page
6233
Abstract
An efficient method of palladium-catalyzed direct 5-arylation of 1,3-dimethyluracil was developed with a various range of aryl bromides including electron-deficient aryl bromides. 5-Aryluracil derivatives were obtained in moderate to good yields regioselectively most likely via an electrophilic metalation–deprotonation process.
Keywords
PALLADIUM , uracil , Direct arylation , Electrophilic metalation–deprotonation
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879575
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