Title of article :
N-Arylation of a hindered indoline as a route to 2-(2-methyl-1-(4-oxo-3,4-dihydrophthalazin-1-yl)-1H-indol-3-yl)acetic acid derivatives
Author/Authors :
Papaioannou، نويسنده , , Nikolaos and Marathias، نويسنده , , Vasilios and Wan، نويسنده , , Zhao-Kui and Kaila، نويسنده , , Neelu and Ali، نويسنده , , Zahid and Saiah، نويسنده , , Eddine، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Pages :
4
From page :
6317
To page :
6320
Abstract :
A convenient synthesis of 2-(2-methyl-1-(4-oxo-3,4-dihydrophthalazin-1-yl)-1H-indol-3-yl)acetic acid derivatives is described using a microwave-promoted multi-step SNAr reaction. The desired products were found to exhibit atropisomerism.
Keywords :
CRTh2 , Microwave-assisted , Atropisomer , Indole acetic acid , Indoline
Journal title :
Tetrahedron Letters
Serial Year :
2011
Journal title :
Tetrahedron Letters
Record number :
1879593
Link To Document :
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