Title of article :
Continuous flow biocatalytic resolutions of methyl sulfinylacetates
Author/Authors :
Liu، نويسنده , , Zhanxiang and Burgess، نويسنده , , Kevin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Product inhibition was encountered for some substrates in the resolution of methyl sulfinylacetates mediated by lipase Amano AK, so an apparatus to continually extract the carboxylate product was devised. This was applied to resolve some sulfoxides with high enantiodifferentiation.
Keywords :
Biocatalytic resolution , Lipase , Sulfoxide
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters