Title of article
A concise total synthesis of bruceolline E
Author/Authors
Jordan، نويسنده , , Jason A. and Gribble، نويسنده , , Gordon W. and Badenock، نويسنده , , Jeanese C.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
6772
To page
6774
Abstract
An efficient synthesis of bruceolline E was completed in three steps from the known ethyl indole-1-carboxylate (9d) in 60% overall yield, via a tandem acylation/Nazarov cyclization with 3,3-dimethyl acrylic acid followed by selenium dioxide oxidation to install the α-diketone functionality.
Keywords
Bruceolline E , Nazarov cyclization , selenium dioxide , indole
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879707
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