Title of article :
Novel acid-mediated reactions of phenyl-substituted lactams
Author/Authors :
King، نويسنده , , Frank D. and Caddick، نويسنده , , Stephen، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Treatment of 3-phenylazetidin-2-one and 7-phenylazepin-2-one with triflic acid in benzene gave a novel, high yielding conversion to 3,3-diphenylpropionamide and 6,6-diphenylhexanoic acid amide, respectively. However, with AlCl3, 7-phenylazepin-2-one was converted into 3-phenylazepin-2-one via a retro-Beckman rearrangement.
Keywords :
Retro-Beckman , Rearrangement , Lactam , Aluminium chloride , Triflic acid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
