Author/Authors :
Wang، نويسنده , , Xiang and Guram، نويسنده , , Anil and Ronk، نويسنده , , Michael and Milne، نويسنده , , Jacqueline E. and Tedrow، نويسنده , , Jason S. and Faul، نويسنده , , Margaret M.، نويسنده ,
Abstract :
This Letter describes a copper catalyzed sulfonamide coupling reaction with aryl bromides to form N-aryl sulfonamides under mild conditions, including the first examples of Cu-catalyzed sulfonamide coupling at room temperature. The reaction protocol tolerates a broad range of substrates including a variety of primary and secondary sulfonamides and challenging heteroaryl bromides such as 2-bromothiazole.
