Author/Authors :
Haridas، نويسنده , , V. and Sadanandan، نويسنده , , Sandhya and Sharma، نويسنده , , Yogesh K. and Chinthalapalli، نويسنده , , Srinivas and Shandilya، نويسنده , , Ashutosh، نويسنده ,
Abstract :
Here we describe bispidine as a scaffold for inducing open turn-like and beta sheet conformations on the attached peptides depending on the mode of attachment of peptides to the scaffold. Various bispidine–peptide conjugates were designed and synthesized to demonstrate the versatility of the scaffold.
Keywords :
Bispidine , secondary structure , Peptide , Beta turn , beta sheet