Author/Authors :
Seganish، نويسنده , , W. Michael and Bercovici، نويسنده , , Ana and Ho، نويسنده , , Ginny D. and Loozen، نويسنده , , Hubert J.J. and Timmers، نويسنده , , Cornelis M. and Tulshian، نويسنده , , Deen، نويسنده ,
Abstract :
A flexible route to analogues of dihydroimidazo[5,1-a]isoquinolines is described. The synthesis hinges on a sequential Ugi coupling, followed by a Bischler–Napieralski reaction to form the imidazole isoquinoline core. This route facilitates the introduction of a range of substitutions throughout the carbon framework.
